D. Thibaut, F. Kiuchi, L. Debussche, F. Blanche, M. Kodera, F. J. Leeper and A. R. Battersby
"Biosynthesis of Vitamin B12: Structural Studies on Precorrin-8x, an Octamethylated Intermediate and the Structure of its Stable Tautomer"
J. Chem. Soc., Chem. Commun.,1992, 982-985. Full Text
The structure of precorrin-8x, the octamethylated B12 intermediate which follows precorrin-6y in Pseudomonas denitrificans, is largely determined by 13C-labelling and NMR spectroscopy and the structure of its most stable tautomer is established.
Department of Chemistry
University of Cambridge