Leeper Group



J. M. Bulsing, E. D. Laue, F. J. Leeper, J. Staunton, D. H. Davies, G. A. F. Ritchie, A. Davies, A. B. Davies and R. P. Mabelis
"Biosynthesis of the Polyketide Antibiotic ICI 139603 in Streptomyces longisporoflavus: Assignment of the 13C NMR by Two-Dimensional Methods and Determination of the Origin of the Carbon Atoms"
J. Chem. Soc., Chem. Commun.,1984, 1301-1302. Full Text

The carbon skeleton of the polyether antibiotic lCI139603 (1) is shown to consist of a polyketide chain, derived from seven acetate units and six propionate units, combined with a C2-unit of unknown origin.

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Department of Chemistry
University of Cambridge