Leeper Group



A. I. D. Alanine, Y. Li, N. P. J. Stamford, F. J. Leeper, F. Blanche, L. Debussche and A. R. Battersby
"Biosynthesis of Vitamin B12: Studies of the Oxidative and Lactone-forming Steps by 18O-Labelling"
J. Chem. Soc., Chem. Commun.,1994, 1649-1650. Full Text

Experiments based on the use of 18O2 and electrospray mass spectrometry show that during the conversion of precorrin-3A into precorrin-3B or precorrin-4 just one atom of oxygen is incorporated.

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Department of Chemistry
University of Cambridge