Leeper Group



F. J. Leeper and D. H. C. Smith
"Synthesis and Structure of Bridged Thiazolium Salts"
Tetrahedron Lett.,1988, 29, 1325-1328. Full Text

Bridged thiazolium salts (6, n = 4 and 5) have been synthesized using macrolactonisation techniques to make the corresponding thiazolinethiones followed by treatment with H2O2. For each compound the bridge exists predominantly in a single conformation which has been determined both by n.m.r. and X-ray crystallography.

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Department of Chemistry
University of Cambridge