Abstract

99
R. L. Knight and F. J. Leeper
"Comparison of chiral thiazolium and triazolium salts as asymmetric catalysts for the benzoin condensation"
J. Chem. Soc., Perkin Trans. 1,1998, 1891-1893. Full Text

Chiral bicyclic 1,2,4-triazolium salts having a defined face of the heterocyclic ring hindered have been synthesised and they catalyse the benzoin condensation in good yield; the enantiomeric excesses obtained (up to 80%) are much better than with closely related thiazolium salts and the opposite enantiomer of benzoin predominates.

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