Leeper Group



I. M. Bell, C. Abell and F. J. Leeper
"Design and Synthesis of Transition State Analogues for a Cationic Cyclisation"
J. Chem. Soc., Perkin Trans.1,1994, 1997-2006. Full Text

Transition-state analogues based upon the 6-(hydroxymethyl)-13-azagona-1,3,5(10),8-tetraene structure have been designed and synthesized as part of a programme to elicit antibodies capable of catalysing cationic cyclisations. Methodology for conjugating such analogues to proteins has also been developed.

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Department of Chemistry
University of Cambridge